Regional Cleft Lip and Palate Center

Principle contact details

Contact name:Gian Luca Gatti
Address:Via Roma, 67
56126 Pisa PI - Italy
Country:Italy
Telephone:39050996777
Email:glgatti@gmail.com
Web address:Visit website

Other team members

Surgeon:Gian Luca Gatti (Plastic Surgeon) Alessandro Giacomina (Plastic Surgeon)
Speech therapist:Renata Salvadorini
Orthodontist:Sara Bigagli
Clinical geneticist:Benedetta Toschi
Otolaryngologist:Francesca Forli
Psychologist:Ciro Conversano
Other:Beate Kuppers - anesthesiologist and pediatrician

Support group

Support group contact name:AISMEL - OnlusVia Montanara, 14 56012 Cascina, PisaMail: aismel.info@gmail.comhttp://www.labiopalatoschisi.eu/

Annual case load

Cleft palate:10 +/-
Cleft lip & palate (CLP) Unilateral (UCLP):+/- 50
Bilateral (BCLP):+/- 20

Primary surgical protocol

Timing of first repair and type of operation.

Complete UCLP:2,5/3 months - Modified Tennison technique
Complete BCLP:2,5/3 months - Mulliken technique
Isolated CP:6 months - Bardach technique

Record collection protocol

Are records routinely collected at specific ages?Yes
Does this conform to WHO timing recommendations
(birth, 5, 10, 15 and 20 years)?
Yes

State coverage of costs

Are the costs of the following treatments covered by the state (free to the patient)?

Surgery costs:All
Orthodontic costs:All
Speech and language therapy costs:All
Comments on the service provision:In Italy all the cost are provided by the NHS.

However families can decide if they want to go to a private practice.

Clinical research

Clinical team members who are or would like to be involved in clinical research:

Member details:we would be happy to be involved in inter-centre comparisons, cohort studies, clinical trials.

Gian Luca Gatti - plastic surgeon
Alessandro Giacomina - plastic surgeon
Luca Rosato - plastic surgeon
Beate Kuppers - anesthesiologist
Sara Bigagli - orthodontist

Current research activity and data collection

Type(s) of software used:Excel and Word.
Published research papers:Yes
Details of publications:Scand J Plast Reconstr Surg Hand Surg. 2010 Apr;44(2):88-95. doi: 10.3109/02844310903569378.
Effect of lip adhesion on maxillary arch alignment and reduction of a cleft's width before definitive cheilognathoplasty in unilateral and bilateral complete cleft lip.
Gatti GL1, Lazzeri D, Romeo G, Balmelli B, Massei A.

Cleft Palate Craniofac J. 2009 Nov;46(6):621-8. doi: 10.1597/08-085.1. Epub 2009 May 16.
Bone regeneration and periosteoplasty: a 250-year-long history.
Lazzeri D1, Gatti GL, Romeo G, Balmelli B, Massei A.

Cleft Palate Craniofac J. 2008 Nov;45(6):587-91. doi: 10.1597/07-026.1. Epub 2007 Aug 21.

Dystrophic-like alterations characterize orbicularis oris and palatopharyngeal muscles in patients affected by cleft lip and palate.
Lazzeri D1, Viacava P, Pollina LE, Sansevero S, Lorenzetti F, Balmelli B, Funel N, Gatti GL, Naccarato AG, Massei A.

Thyroid. 2004 Aug;14(8):584-8.
Genetic analysis of TTF-2 gene in children with congenital hypothyroidism and cleft palate, congenital hypothyroidism, or isolated cleft palate.
Tonacchera M1, Banco M, Lapi P, Di Cosmo C, Perri A, Montanelli L, Moschini L, Gatti G, Gandini D, Massei A, Agretti P, De Marco G, Vitti P, Chiovato L, Pinchera A.
Willing to share Powerpoint presentations:Yes

Potential clinical research activities

Clinical research activities interested in being involved in:

Randomised clinical trials:Yes
Inter-centre comparison of outcome:Yes
Prospective study:Yes
DNA collection:Yes

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:

Laboratory genetics/genomics research:Yes
Animal models research:Yes

National cleft lip and palate / craniofacial scientific organisation

Organisation details:silpsitalia@yahoo.it

http://www.silps.it/

Total number of cases per annum

Total cases per annum:90 +/-