Smile House (Regional Center for CLP San Paolo Hospital, Milano) Azienda Ospedaliera San Paolo 20142 Milano
Principle contact details
| Contact name: | Roberto Brusati and Giovanna Garattini |
| Address: | Via Antonio di Rudinì 8, 20142 Milano, Italy |
| Country: | Italy |
| Telephone: | 39.02818439 |
| Email: | segreteriasmilehouse@ao-sanpaolo.it |
| Web address: | Visit website |
Other team members
| Surgeon: | Roberto Brusati, Luca Autelitano |
| Speech therapist: | Angela Rezzonico |
| Orthodontist: | Giovanna Garattini and Costanza Meazzini |
| Otolaryngologist: | Giovanni Felisati |
| Specialist nurse: | Ornella Squaratti |
| Psychologist: | Egidio Moja |
| Patient follow up: | All the team |
Support group
| Support group address: | Gruppo Genitori San Paolo Roberto Maspes E-mail: info@tiraccontounsorriso.it Website: www.tiraccontounsorriso.it |
Annual case load
| Cleft palate: | 27 cases of 2011 |
| Cleft lip (CL) Unilateral (UCL): | 13 cases of 2011 |
| Bilateral (BCL): | 9 cases of 2011 |
| Number of syndromic cases: | 13 cases of 2011 |
Primary surgical protocol
Timing of first repair and type of operation.
| Complete UCLP: | 4-6 months lip, nose, soft palate; 18-24 months hard palate and GAP; 4-6 months less than 10 cm all in one |
| Complete BCLP: | 4-6 months lip, nose, soft palate; 18-24 months hard palate and GA P |
| Isolated CP: | 10-12 months |
Record collection protocol
| Are records routinely collected at specific ages? | Yes |
| Does this conform to WHO timing recommendations (birth, 5, 10, 15 and 20 years)? | Yes |
State coverage of costs
Are the costs of the following treatments covered by the state (free to the patient)?
| Surgery costs: | All |
| Orthodontic costs: | Part |
| Speech and language therapy costs: | All |
Clinical research
Clinical team members who are or would like to be involved in clinical research:
| Member details: | BRUSATI - SURGERY - Clinical trials GARATTINI - ORTHO - MEAZZINI - ORTHO - |
Current research activity and data collection
| Type(s) of software used: | Word, Excel |
| Details of publications: | 1: Brusati R, Colletti G. The role of maxillary osteotomy in the treatment of arhinia. J Oral Maxillofac Surg. 2012 May;70(5):e361-8. Epub 2012 Feb 23. PubMed PMID: 22364860. 2: Meazzini MC, Allevia F, Mazzoleni F, Ferrari L, Pagnoni M, Iannetti G, Bozzetti A, Brusati R. Long-term follow-up of syndromic craniosynostosis after Le Fort III halo distraction: a cephalometric and CT evaluation. J Plast Reconstr Aesthet Surg. 2012 Apr;65(4):464-72. Epub 2012 Jan 9. PubMed PMID: 22227504. 3: Meazzini MC, Tortora C, Morabito A, Garattini G, Brusati R. Factors that affect variability in impairment of maxillary growth in patients with cleft lip and palate treated using the same surgical protocol. J Plast Surg Hand Surg. 2011 Sep;45(4-5):188-93. PubMed PMID: 22150138. 4: Montirosso R, Fedeli C, Murray L, Morandi F, Brusati R, Perego GG, Borgatti R. The role of negative maternal affective states and infant temperament in early interactions between infants with cleft lip and their mothers. J Pediatr Psychol. 2012 Mar;37(2):241-50. Epub 2011 Oct 17. PubMed PMID: 22004886. 5: Cesaretti C, Gentilin B, Bianchi V, Melloni G, Bonaguro M, Rossi C, Meazzini C, Brusati R, Lalatta F. Occurrence of complete arhinia in two siblings with a clinical picture of Treacher Collins syndrome negative for TCOF1, POLR1D and POLR1C mutations. Clin Dysmorphol. 2011 Oct;20(4):229-31. PubMed PMID: 21772136. 6: Meazzini MC, Brusati R, Caprioglio A, Diner P, Garattini G, Giannì E, Lalatta F, Poggio C, Sesenna E, Silvestri A, Tomat C. True hemifacial microsomia and hemimandibular hypoplasia with condylar-coronoid collapse: diagnostic and prognostic differences. Am J Orthod Dentofacial Orthop. 2011 May;139(5):e435-47. PubMed PMID: 21536185. 8: Meazzini MC, Mazzoleni F, Bozzetti A, Brusati R. Comparison of mandibular vertical growth in hemifacial microsomia patients treated with early distraction or not treated: follow up till the completion of growth. J Craniomaxillofac Surg. 2012 Feb;40(2):105-11. Epub 2011 Mar 31. PubMed PMID: 21454084. 11: Meazzini M, Lematti L, Mazzoleni F, Rabbiosi D, Bozzetti A, Brusati R. Vertical excess of the premaxilla in bilateral cleft lip and palate patients: a protocol for treatment. J Craniofac Surg. 2010 Mar;21(2):499-502. PubMed PMID: 20489454. 12: Meazzini MC, Brusati R, Diner P, Giannì E, Lalatta F, Magri AS, Picard A, Sesenna E. The importance of a differential diagnosis between true hemifacial microsomia and pseudo-hemifacial microsomia in the post-surgical long-term prognosis. J Craniomaxillofac Surg. 2011 Jan;39(1):10-6. Epub 2010 Apr 24. PubMed PMID: 20456963. 13: Meazzini MC, Rossetti G, Morabito A, Garattini G, Brusati R. Photometric evaluation of bilateral cleft lip and palate patients after primary columella lengthening. Cleft Palate Craniofac J. 2010 Jan;47(1):58-65. PubMed PMID: 19860518. 14: Meazzini MC, Rossetti G, Garattini G, Semb G, Brusati R. Early secondary gingivo-alveolo-plasty in the treatment of unilateral cleft lip and palate patients: 20 years experience. J Craniomaxillofac Surg. 2010 Apr;38(3):185-91. Epub 2009 Jul 9. PubMed PMID: 19589688. 16: Brusati R, Pedrazzoli M, Colletti G. Functional results after condylectomy in active laterognathia. J Craniomaxillofac Surg. 2010 Apr;38(3):179-84. Epub 2009 Jun 5. PubMed PMID: 19501516. 17: Brusati R, Donati V, Marelli S, Ferrari M. Management of a case of arhinia. J Plast Reconstr Aesthet Surg. 2009 Jul;62(7):e206-10. Epub 2009 Apr 26. PubMed PMID: 19401274. 19: Meazzini MC, Capasso E, Morabito A, Garattini G, Brusati R. Comparison of growth results in patients with unilateral cleft lip and palate after early secondary gingivoalveoloplasty and secondary bone grafting: 20 years follow up. Scand J Plast Reconstr Surg Hand Surg. 2008;42(6):290-5. PubMed PMID: 18991170. 20: Meazzini MC, Giussani G, Morabito A, Semb G, Garattini G, Brusati R. A cephalometric intercenter comparison of patients with unilateral cleft lip and palate: analysis at 5 and 10 years of age and long term. Cleft Palate Craniofac J. 2008 Nov;45(6):654-60. Epub 2008 Feb 20. PubMed PMID: 18956937. 22: Del Guercio F, Meazzini MC, Garattini G, Morabito A, Semb G, Brusati R. A cephalometric intercentre comparison of patients with unilateral cleft lip and palate at 5 and 10 years of age. Eur J Orthod. 2010 Feb;32(1):24-7. Epub 2008 Sep 27. PubMed PMID: 18820305. 23: Meazzini MC, Donati V, Garattini G, Brusati R. Maxillary growth impairment in cleft lip and palate patients: a simplified approach in the search for a cause. J Craniofac Surg. 2008 Sep;19(5):1302-7. PubMed PMID: 18812855. 25: Meazzini MC, Mazzoleni F, Bozzetti A, Brusati R. Does functional appliance treatment truly improve stability of mandibular vertical distraction osteogenesis in hemifacial microsomia? J Craniomaxillofac Surg. 2008 Oct;36(7):384-9. Epub 2008 Apr 28. PubMed PMID: 18442918. 26: Tortora C, Meazzini MC, Garattini G, Brusati R. Prevalence of abnormalities in dental structure, position, and eruption pattern in a population of unilateral and bilateral cleft lip and palate patients. Cleft Palate Craniofac J. 2008 Mar;45(2):154-62. PubMed PMID: 18333651. |
| Research grant funding received: | Yes |
| Details of funding: | EUROCLEFT AND EUROCRAN |
| Willing to share Powerpoint presentations: | Yes |
EU Biobank
Stored CLP DNA samples available for use in future studies:
| Number for CP: | *** please ask to professor Michele Rubini (rub@unife.it) |
Potential clinical research activities
Clinical research activities interested in being involved in:
| Randomised clinical trials: | Yes |
| Inter-centre comparison of outcome: | Yes |
National cleft lip and palate / craniofacial scientific organisation
| Organisation details: | S.I.L.P.S, www.silps.it COSTANZA MEAZZINI (cmeazzini@yahoo.it) |