Groupe pour le traitement des fentes labio-maxillo-palatines

Principle contact details

Contact name:PD Dr Giorgio C. La Scala
Address:Chirurgie Pédiatrique Plastique
Clinique de Chirurgie Pédiatrique
Départment de l'enfant et de l'adolescent
Hôpital des Enfants – Hôpitaux Universitaires de Genève
5 rue Willy-Donzé
CH 1205 Genève
Web address:Visit website

Map of location

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Other team members

Surgeon:PD Dr Giorgio La Scala; Dr Emmanuelle Dorie
Speech therapist:Ms Sonia Alberton Zanasco
Orthodontist:Dr Georges Herzog; Dr Gregory Antonarakis, PhD
Clinical geneticist:Dr Armand Bottani
Otolaryngologist:Dr Igor Leuchter (Phoniatry), Dr Hélène Cao Van
Specialist nurse:Vacant
Other:Pr Dr Paolo Scolozzi (Maxillo-facial surgery)
Patient follow up:PD Dr Giorgio La Scala, Dr Georges Herzog

Support group

Support group address:Bouche à Oreille -

Annual case load

Cleft palate:6
Pierre Robin:1
Cleft lip (CL) Unilateral (UCL):1
Bilateral (BCL):2
Number of syndromic cases:~10%

Primary surgical protocol

Timing of first repair and type of operation.

Complete UCLP:3 m CL, 12 m CP repair, 8-10 y alveolar bone graft
Complete BCLP:3 m BCL, 12 m CP repair, 8-10 y alveolar bone graft
Isolated CP:12 m

Record collection protocol

Are records routinely collected at specific ages?Yes
What record taking protocol is used:Birth-7-10-15-20 years

State coverage of costs

Are the costs of the following treatments covered by the state (free to the patient)?

Surgery costs:All
Orthodontic costs:All
Speech and language therapy costs:All

Clinical research

Clinical team members who are or would like to be involved in clinical research:

Member details:G La Scala - Ped Plast Surg - Swiss Nat'l Registry
I Leuchter - PhoniatricsENT -
G Antonarakis - Orthodontics -

Non-clinical and laboratory research

Non-clinical and laboratory team members who are or would like to be involved in clinical research:

Member details:........................... - Genetics - ....................

Current research activity and data collection

Type(s) of software used:• Swiss National Cleft Registry
• Prospective data collection for all centre patients
• Role of mitochondria in cleft palate (In association with Hospital for Sick Children, Toronto, Canada)

Proprietary, Cardiff Teleform, Excel-Access
Participation in other collaborations (projects):Yes
Details of projects:Swiss Cleft Network (Geneva - Bern)

EU Biobank

Stored CLP DNA samples available for use in future studies:

Number for CP:All our patients have a blood sample taken for possible genetic analysis that CANNOT however be performed without their written consent.

Potential clinical research activities

Clinical research activities interested in being involved in:

Randomised clinical trials:Yes
Inter-centre comparison of outcome:Yes
Prospective study:Yes
DNA collection:Yes

Potential laboratory based research activities

Laboratory based research activities interested in being involved in:

Laboratory genetics/genomics research:Yes
Animal models research:Yes

National cleft lip and palate / craniofacial scientific organisation

Organisation details:SGLKG -

Useful websites or links

Useful websites or links:Swiss Cleft Registry -

Total number of cases per annum

Total cases per annum:12 on average (below last 12)