Ankara University, School of Dentistry, Department of Orthodontics
Principle contact details
| Contact name: | Dr. Ayşe Tuba Altuğ |
| Address: | Ankara Universitesi Dis Hekimligi Fakultesi Ortodonti Anabilim Dali, 06500, Besevler, Ankara, Turkey. |
| Country: | Turkey |
| Telephone: | 0090(312)2965654 Mobile: 0090(532)4361641 |
| Email: | aysealtug@yahoo.com |
| Web address: | Visit website |
Other team members
| Surgeon: | Dr. Ayşegül Tüzüner Öncül (Ankara University, School of Dentistry, Department of Oral and Maxillofacial Surgery); Various surgeons of Ankara University, School of Dentistry, Department of Oral and Maxillofacial Surgery; Various surgeons of Ankara University, Medical School, Department of Plastic and Reconstructive Surgery; Various surgeons of Hacettepe University, Medical School, Department of Plastic and Reconstructive Surgery |
| Orthodontist: | Dr. Ayşe Tuba Altuğ, Dr. Ufuk Toygar Memikoğlu, Dr. Okan Akçam, Dr. Aslı Şenol, Dr. Ani Türköz |
| Clinical geneticist: | Dr. Serdar Ceylaner, Dr. Gülay Ceylaner |
| Patient follow up: | Dr. Aslı Şenol, Dr. Ani Türköz |
Annual case load
| Cleft palate: | Approx. 15-20 infant (incl. Pierre Robin) Various numbers of routine orthodontics cases with cleft at different age. |
| Cleft lip (CL) Unilateral (UCL): | Approx. 15-20 infant (incl. Pierre Robin) Various numbers of routine orthodontics cases with cleft at different age. |
| Bilateral (BCL): | Approx. 15-20 infant |
| Number of syndromic cases: | (Syndomes including cleft) Approx. %30 of all cases |
Primary surgical protocol
Timing of first repair and type of operation.
| Complete UCLP: | 4-5 months (Mulliken, Delaire) |
| Complete BCLP: | 5-6 months (Mulliken, Millard) |
| Isolated CP: | 8 months soft palate repair 12-18 months hard palate repair For all clefts types; approx. age 9-10 secondary bone grafting Approx. 18 age Le Fort I or Bimaxillary Surgery |
Record collection protocol
| What record taking protocol is used: | Cast and photographs at birth and during pre-primary surgery orthodontics, routine orthodontic records before maxillary advancement therapy by face-mask (at age 7-8), computerized tomography before secondary bone grafting, routine ortho. records before Le Fort 1 surgery if needed. |
State coverage of costs
Are the costs of the following treatments covered by the state (free to the patient)?
| Surgery costs: | Part |
| Orthodontic costs: | Part |
| Speech and language therapy costs: | Part |
Clinical research
Clinical team members who are or would like to be involved in clinical research:
| Member details: | Ayşe Altuğ - Orthodontics - Associate Prof. Former Research fellow (2000-2001) at NYU-IRPS, New York, USA Ufuk Memikoğlu - Orthodontics - Professor Okan Akçam - Orthodontist - Professor Ayşegül Tüzüner - Oral and Maxillofacial Surgery - Associate Prof. Former Research Fellow QEII Health Sciences Centre Halifax, Canada Aslı Şenol - Orthodontics - Doctorate Student |
Non-clinical and laboratory research
Non-clinical and laboratory team members who are or would like to be involved in clinical research:
| Member details: | Ayşe Altuğ - Orthodontics - Associate Prof. Former Research fellow (2000-2001) at NYU-IRPS, New York, USA Ufuk Memikoğlu - Orthodontics - Professor Okan Akçam - Orthodontist - Professor Ayşegül Tüzüner - Oral and Maxillofacial Surgery - Associate Prof. Former Research Fellow QEII Health Sciences Centre Halifax, Canada Aslı Şenol - Orthodontics - Doctorate Student |
Current research activity and data collection
| Type(s) of software used: | Any kind |
| Participation in inter-centre studies: | Yes |
| Details of studies: | Distraction Osteogenesis studies with NYU Genetic Studies with Private Genetics Center Various studies with other universities on Cleft. |
| Participation in other collaborations (projects): | Yes |
| Details of projects: | Genetic Studies with Private Genetics Center |
| Published research papers: | Yes |
| Details of publications: | The senior members of the team each has approximately 20 published papers. |
| Willing to share Powerpoint presentations: | Yes |
EU Biobank
Stored CLP DNA samples available for use in future studies:
| Number for CP: | We are also building up a genetic sample of various types of Cleft at the moment. We would be happy to get involved in such a DNA based study in the future. |
Potential clinical research activities
Clinical research activities interested in being involved in:
| Randomised clinical trials: | Yes |
| Inter-centre comparison of outcome: | Yes |
| Prospective study: | Yes |
| DNA collection: | Yes |
Potential laboratory based research activities
Laboratory based research activities interested in being involved in:
| Laboratory genetics/genomics research: | Yes |